Thyroid Nutrition for Optimal Thyroid Health – The Adrenal, Gut, Brain and Thyroid Connection

Thyroid Nutrition for Optimal Thyroid Health - The Adrenal, Gut, Brain and Thyroid Connection



you hey there it's not to Justin market Johnny and today's talk is in the beyond nutrition for your thyroids how important nutrients and nutrition are for healthy thyroid function we'll do a brief overview of how the thyroid works in case you haven't seen any of my past videos on the thyroid just so you have some foundational info so you can see how a healthy thyroid works and then what you need or what maybe you're missing that's preventing your thyroid from functioning optimally on the nutritional side so let's dig in again steps for healthy thyroid hormone production so let's outline how the thyroid hormonal cascade or Domino rally works so the first step we have is really the brain signaling down to the thyroid like this this pathway is known as her TSH or a thyroid stimulating hormone where TSH is coming from the brain particularly the pituitary and it's telling the thyroid to make thyroid hormone now from there our thyroid then spits out some t4 and about 20% of that t4 actually gets converted to t3 at the thyroid about 20% and we'll review some of the nutrients that we need to help that conversion so 20% actually happens in the thyroid gland the other 80 percent actually happens peripherally so we look down here at that 80% 60% of that 80 actually happens here at the liver so healthy liver function is very important so if we're getting toxins in our food chemicals various plastics we're not getting enough sulfur-based amino acids or antioxidants in our diet to run those pathways our liver may be burdened and that may affect our body's ability to convert and activate thyroid hormone one of the enzymes that's responsible for thyroid conversion the 5di today's enzyme you break it down 5di to mace and di is iodine off so the tea and the number four stands for how many iodine's there are the four stands for number iodine's so we're de I donate something we're pulling an iodine off it that's why it goes from t4 to t3 because we're pulling one iodine molecule off it and we're doing it with that liver based enzyme known as the five deiodinases enzyme which is selenium based so things like egg yolks seafood nuts seeds things like that are going to be very rich in selenium which we're going to need for for that liver enzyme to work and selenium is also a strong precursor to glutathione so selenium also helps with our toxification also supports the liver liver is very important for thyroid hormone conversion next we see gut bacteria we need good healthy gut bacteria because about 20% of conversion is responsible in and around the gut with acetic acid or the various sulphate ace enzymes these enzymes are important at taking in activated t3 and activating it so if you have dysbiosis or imbalances and gut bacteria from various infections pathogens or even small intestinal bacterial overgrowth that can throw off the balance of your gut bacteria and that can decrease your guts ability to activate thyroid hormone next is the adrenal glands the adrenals are profound very very important for activation of thyroid hormone mainly because of the fact that if we're under adrenal stress that can increase our reverse t3 levels so really simple I count the adrenals as being a 20% contributor of activating thyroid hormone it does it a couple of ways if the body is under too much stress cortisol is too high we have high cortisol will have more reverse t3 and reverse t3 is inactive t3 so inactive t3 imagine this being our receptor site here let me pull out a different color so you can see it better if this is our receptor site here this is our receptor site for our thyroid hormone okay that's our cell and if this is reverse t3 here like so and let's just draw a molecule here t3 like so what happens is this reverse t3 molecule gets in the receptor site like so doesn't have the same metabolic effect of the t3 so the t3 can't make its way into the receptor site because the receptor site is blocked so that's kind of how reverse t3 works it's like taking a gun and putting bullets in the magazine to that gun that are blanks so you go to fire get fire that gun and the effect that you're looking for is that bullet to come out but all you hear is the noise but you don't get the actual end result same thing metabolically we see a hormone in that receptor site but it's a hormone that doesn't have the same type of stimuli stimulation that thyroid hormone does at the nuclear receptor site level so on that note we need healthy levels of cortisol for thyroid conversion to happen so the adrenals also affected because high levels of cortisol stress etc this can actually affect TSH TSH levels can go off with extreme amount of stress via cortisol and if we're depleted if our adrenals are so dysfunctional where cortisol levels are now low like at a stage 3 adrenal fatigue person then if that low levels present we're not going to have enough cortisol to make that conversion happen and we need cortisol to really activate that thyroid hormone when we do thyroid temperature testing will see chronically low temperatures with low thyroid function when we see adrenal stress will see aberrations and temperature greater than 0.3 degrees Fahrenheit so what we'll see when we have adrenal and thyroid is if this is the threshold we want to be at temperature wise we'll have low temperature but we'll have aberrations in low temperature if it's just straight low temperature that's a thyroid dysfunction if it's low and aberrant that's thyroid adrenals and if it's normal and aberrant that's just adrenal function so that's a great way that you can use temperature to assess whether you have a thyroid adrenal issue or both so on that note now that everyone has a good background of how the thyroid gland is converting a lot of these t4 and t3 into active hormone now that you have that foundation let's talk about some of the nutrients that are involved for activating thyroid hormone so first off we have TSH the brain needs vitamin A it needs zinc it needs B vitamins it needs protein a spur gene the various amino acids to make our TSH that's the signal er so TSH is an inverse hormone it goes high when thyroid hormone is low and it goes low when thyroid hormone is high essentially so if I'm yelling at someone I'm not getting their attention off to raise my voice louder til I get their attention think of that what TSH is doing the brain is yelling down to the thyroid to make hormone and if it's not high enough it will increase the amount of TSH a very bad indicator to use for thyroid dysfunction because it's so late stage it comes on so late in the game five to ten years down the road we really want to be looking at the actual active hormone downstream the t3 that's activated down here this is much more important and much more indicative of an early stage thyroid issue and a lot of times people may have fine levels of TSH because t4 feeds back into the brain better than t3 we could have normal levels of t4 but have low levels of t3 and it may not even be reflected in the TSH I see that all the time my patients that's all we got to be very careful we actually have to look at t sh t for free in total t3 free in total and maybe even look at reverse t3 as well and the thyroid antibodies so again we talked about the nutrition vitamin a zinc various B vitamins and protein for healthy thyroid hormone function knocking that first domino over which is TSH and again if we have a gut issue you can see nutrition isn't just a given if we take in nutrient-rich foods but we have a gut issue in a malabsorption and low stomach acid and dysbiosis and infections you can see how that may impede the absorption of these new treants thus causing deficiency even though we're having a really good diet intact so keep that in mind we always got to look deeper at the gut deeper at the liver and deeper at the adrenals we can't ignore these three body systems next is t4 so iodine is an important nutrient for thyroid hormone creation so the process known as a donation involves iodine and tyrosine being cleaved together so the T actually stands for in t4 or t3 it stands for tyrosine cannot thyroid with tyrosine that's an amino acid and the four and the three stand for the number of iodine's so we don't need too much iodine to have this healthy conversion at this activation there's a lot of debate out there that we need more you know into the milligram high milligram range some say we only need the RDA a couple hundred micrograms 250 or so to be exact to make our thyroid hormone again we got to be careful because iodine can be a strong stimulator of autoimmunity it's a great deal of research showing that excess iodine can actually stimulate Hashimoto's it activates tpo or thyroglobulin antibodies that can increase thyroid destruction again a lot of people say that the reason why iodine is a contributing issue with autoimmune conditions is because people also are very very low in selenium and when our iodine when iodine is being fused to thyroid hormone via this process known as IO donation what happened as a result is hydrogen peroxide gets kicked out and this hydrogen peroxide can be very inflammatory and can cause our b-cells to come up and infiltrate and start attacking the thyroid tissue so that's why if you're giving any amount of select if you're giving any amount of iodine you want to make sure there are adequate levels of selenium there because selenium comes in and it actually neutralizes the hydrogen peroxide pulls an oxygen off it and makes it h2o which is water which is very benign so you can see giving iodine and not having selenium their bites side can definitely be a recipe for destruction so with iodine be very careful of it make sure you're working with a functional medicine doctor make sure you're not autoimmune or have any autoimmune before you give iodine at higher levels a couple hundred mics will probably be okay but double-check with your functional medicine doctor again you can see irons really important if you have a microcytic hypochromic anemia that's going to be a major issue low iron we need iron to make thyroid hormone but we also need iron to help carry oxygen throughout our body B vitamins b6 is super important because b6 helps with dopamine activation and if we go up one stream here and we look at like let's say the hypothalamus which is the top part of the brain we actually need dopamine from the hypo dopamine production actually stimulate the hypothalamus to make trh and trh is important at stimulating TSH so dopamine is essential and a lot of people may have neurotransmitter issues that need to be fretted out doing a in depth organic acid test so iodine tyrosine iron b6 your B vitamins really important for energy for making the krebs cycle go around I did a video on the mitochondria recently take a look at that video to get more info on B vitamins vitamin C's are really important antioxidant and helps the adrenals as well and vitamin D is really important for immune function a lot of people with Hashimoto's and hypothyroid autoimmune issues tend to have a vitamin D polymorphism at the receptor side of the vitamin d receptor and they need higher levels of vitamin D 70 to 100 so be very mindful if you have an autoimmune thyroid make sure your vitamin D levels are up at 70 to 100 just to make sure you have that therapeutic immune balancing effect and we already talked about the nutrients needed for t4 to t3 that selenium is essential also for the autoimmune effects of helping to neutralize the hydrogen peroxide into water and then zinc is also very important zinc is important for thyroid conversion zinc is also essential for sex hormone production making testosterone essentially and then also it's an important building block for making hydrochloric acid if we don't have hydrochloric acid levels adequate enough we won't keep at nice low pH in the stomach if we don't have that nice low pH we won't be able to break down protein and fat adequately and we'll have a harder time ionizing minerals we need to ionize minerals and hit them with hydrochloric acid so then we can then take them in our blood so they're not like rocks floating in our bloodstream you actually want to ionize them so they're absorbable so that's really important if we have issues with these nutrients we may see other problems in the thyroid hormone chain that could be happening as well and like I mentioned thought autoimmunity is a big issue 40% of people that test for thyroid autoimmunity actually test they are a false negative they may come back negative but they may still have a positive thyroid so make sure you get your thyroid looked at either palpation wise and or if you need get an ultrasound run just to make sure there are no nodules or inflammation in the thyroid that could be caused by Hashimoto's so outside of that if you have a thyroid issue or a nutritional issue or neurotransmitter issue that could be affecting your thyroid and you're not quite sure the next step to take click on screen again schedule a concept with me subscribe to the videos and get my thyroid hormone balancing series for more information how you can get your thyroid back into balance thanks a lot this is dr j signing off

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